Publications

Obesity wars: hypothalamic sEVs a new hope.

Mukherjee S, Diéguez C, Fernø J, López M.Trends Mol Med. 2023 Aug;29(8):622-634. doi: 10.1016/j.molmed.2023.04.006. Epub 2023 May 18.PMID: 37210227 

Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice.

Milbank E, Dragano N, Vidal-Gómez X, Rivas-Limeres V, Garrido-Gil P, Wertheimer M, Recoquillon S, Pata MP, Labandeira-Garcia JL, Diéguez C, Nogueiras R, Martínez MC, Andriantsitohaina R, López M.Metabolism. 2023 Feb;139:155350. doi: 10.1016/j.metabol.2022.155350. Epub 2022 Nov 21.PMID: 36423694 


Hypothalamic AMPK as a possible target for energy balance-related diseases.

López M.Trends Pharmacol Sci. 2022 Jul;43(7):546-556. doi: 10.1016/j.tips.2022.04.007. Epub 2022 May 12.PMID: 35570061 

Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.

Milbank E, Dragano NRV, González-García I, Garcia MR, Rivas-Limeres V, Perdomo L, Hilairet G, Ruiz-Pino F, Mallegol P, Morgan DA, Iglesias-Rey R, Contreras C, Vergori L, Cuñarro J, Porteiro B, Gavaldà-Navarro A, Oelkrug R, Vidal A, Roa J, Sobrino T, Villarroya F, Diéguez C, Nogueiras R, García-Cáceres C, Tena-Sempere M, Mittag J, Carmen Martínez M, Rahmouni K, Andriantsitohaina R, López M.Nat Metab. 2021 Oct;3(10):1415-1431. doi: 10.1038/s42255-021-00467-8. Epub 2021 Oct 21.PMID: 34675439